Colorectal

A Study of the Safety and Biological Activity of Intraperitoneal (IP) EGEN-001 Administered Alone and in Combination With Standard Chemotherapy in Colorectal Peritoneal Carcinomatosis Patients

Colorectal cancer is the third most commonly diagnosed cancer in both men and women and is the third leading cause of death. Early screening to detect and remove precancerous polyps has resulted in a steady decline in occurrence and death rates associated with the disease and it has been shown that the 5-year survival rate is improved to 90% when detected early in contrast to the 12% 5-year survival rate for late stage detection. Unfortunately, barriers still exits which prevent adequate screening for a significant percentage of the population. During the course of disease progression colorectal cancer frequently can spread in the peritoneal cavity, where it may be amenable EGEN-001 treatment.

More information about colorectal cancer can be found here:
http://www.cancer.gov/cancertopics/types/colon-and-rectal

EGEN-001 colorectal cancer trial